Although Oxandrolone is available
in the U.S. under the brand Oxandrin, it's exorbitant wholesale
price precludes it from entering the black market. Thus, the SPA
version from Italy is the only version left which athlete's do
see regularly. They come 30 tabs to a box, in 2 foil and plastic
strips of 15 each. Oxandrolone has a reputation of being one of
the safest anabolics available. Women and children are often given
this drug with little or no adverse side effects. For athletes,
it is a mild anabolic exerting more strength than muscle mass
increases. Although it is mild, it is 17 alpha alkylated so liver
values may be of concern when used excessively.
Unlike most oral steroids, which
are Class II steroids giving most of their anabolic effect by
means other than the androgen receptor (AR), it seems that oxandrolone
probably does have good binding to the AR, and is therefore a
Class I steroid, while having little other effect. By itself it
is considered to be a weak anabolic.
Partly this is due to its apparent lack of non-AR-mediated activity.
This can be corrected of course by stacking with a Class II steroid
such as Dianabol, Anadrol,
4-AD, or nor-4-AD: the latter two steroids require high blood
levels which are not obtained by oral use of the powders.
The other part of the reason for
this is that bodybuilders make unfortunate and unreasonable comparisons
when judging anabolic steroids. If say 8 tablets per day does
little, then the drug is pronounced useless or weak by the user.
But that is only 20 mg/day, or 140 mg/week. Does 140 mg/week testosterone
give much results? No. Few anabolic steroids give dramatic
results at that dose. Per milligram the potency is reasonable,
but each individual tablet is weak because the dosage is small.
Because of its high price, very
few bodybuilders have taken large doses of oxandrolone. There
is a single case in the medical literature (Forbes et al.) where
it is reported that a competitive athlete self-administered 150
mg oxandrolone per day with remarkable gains. This is of uncertain
credibility because unless urinalysis was done to verify that
no other steroids were taken, there is no way to be certain that
the athlete did not actually take more drugs than he reported.
In any case, at current prices, only the quite wealthy could afford
such a dose. I personally have tried 150 mg/day and considered
it somewhat effective, but not dramatically so, and not a preferred
Oxandrolone does not aromatize or convert to DHT, and has a longer
half life than Dianabol - 8 hours vs. 4 hours. Thus, a moderate
dose taken in the morning is largely out of the system by night,
yet supplies reasonable levels of androgen during the day and
Oxandrolone shares the liver toxicity
problems common to 17-alkylated steroids. At one time it was thought
that it did not, but both clinical and practical experience with
Oxandrin has shown that at doses of 40 mg/day and higher,
liver toxicity is indeed an issue with prolonged use.
Primobolan, I believe, should be
considered a superior compound, offering the same activity at
(usually) a lower price and without the alkylated-toxicity issue.
also see Anavar